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HEPATECTOMY

Hepatectomy is a surgical procedure performed to remove a diseased portion of the liver. The liver is a vital organ responsible for filtering blood, aiding digestion, removing toxins, and producing clotting factors. Since the liver is divided into segments (lobes) and has a remarkable ability to regenerate, a diseased segment can often be safely removed without affecting overall liver function.

Functions of the Liver

The liver plays a critical role in maintaining overall health by:

  • Producing bile for digestion

  • Digesting and storing nutrients such as sugar

  • Removing toxins from the blood

  • Producing proteins required for blood clotting

Conditions Treated with Hepatectomy

Hepatectomy is recommended for various liver conditions, including:

  • Hepatocellular carcinoma (primary liver cancer)

  • Metastatic liver tumors (cancer spread from colon or other organs)

  • Benign liver tumors

  • Hepatolithiasis (stones in the liver bile ducts)

  • Parasitic liver cysts

  • Large liver hemangiomas

  • Chronic or acute liver failure

  • Congenital liver disorders

Diagnosis Before Hepatectomy

Blood Tests

  • Complete Blood Count (CBC)

  • Kidney Function Tests

Liver-Specific Tests

  • Alpha-Fetoprotein (AFP)

    • Elevated levels may indicate liver cancer and are used for diagnosis and follow-up

  • Liver Function Tests (LFTs)

    • Assess liver performance before surgery

  • Blood Clotting Tests (PT, PTT)

    • Evaluate clotting ability, as liver disease can increase bleeding risk

Radiological Investigations

  • Ultrasound

    • Initial assessment of liver damage and tumor extent

  • MRI Scan (with Gadolinium contrast)

    • Differentiates benign and malignant tumors and evaluates blood vessels

  • PET Scan

    • Produces 3D images to assess tumor spread

  • Angiography (CT/MR)

    • Maps liver blood vessels to plan surgery or embolization

  • Radionuclide Scans

    • Bone scan (if cancer spread is suspected)

    • MIBG scan for carcinoid tumors or neuroblastoma

Types of Hepatectomy Procedures

Open Hepatectomy

  • Most commonly performed

  • Incision made below the ribs and mid-abdomen

  • Blood vessels and bile ducts supplying the affected liver segment are isolated

  • Techniques used include ultrasonic surgical aspirator and laser

  • May involve wedge resection, segmentectomy, or lobectomy

Laparoscopic Hepatectomy

  • Minimally invasive surgery using a laparoscope

  • Smaller incisions and faster recovery

  • May be converted to open surgery if complications arise

Partial Hepatectomy

  • Removal of up to 60% of the liver

  • Remaining liver regenerates if healthy

  • Requires careful control of bleeding and bile ducts

Total Hepatectomy

  • Complete removal of the liver

  • Followed by liver transplantation

Outlook After Hepatectomy

  • Liver tumors can be successfully treated with partial hepatectomy or transplantation

  • Early-stage liver cancer has good outcomes

  • Untreated liver cancer can be life-threatening

  • Continuous medical advancements are improving survival rates

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